CBD and Parkinson’s Disease: Potential Benefits and Current Research

CBD and Parkinsons disease

CBD and Parkinson’s Disease: Potential Benefits and Current Research

Parkinson’s disease (PD) affects millions of people worldwide, presenting a significant challenge to patients and healthcare providers alike. As a result, researchers continuously explore new treatment options to improve the lives of those affected. In recent years, cannabidiol (CBD) has emerged as a promising candidate for alleviating some PD symptoms. This article examines the current state of research on CBD and its potential benefits for people living with Parkinson’s disease.

Understanding Parkinson’s Disease

Parkinson’s disease primarily results from the loss of dopamine-producing brain cells in the substantia nigra. Consequently, this loss leads to the characteristic symptoms of PD, which include:

  • Tremors
  • Rigidity
  • Bradykinesia (slowness of movement)
  • Postural instability

In addition to these motor symptoms, PD patients often experience non-motor symptoms such as depression, anxiety, sleep disorders, and cognitive impairment. Therefore, managing Parkinson’s disease requires a comprehensive approach that addresses both motor and non-motor symptoms.

What is CBD?

Cannabidiol, or CBD, is a naturally occurring compound found in the cannabis plant. Unlike its more famous counterpart, tetrahydrocannabinol (THC), CBD does not produce psychoactive effects. As a result, it doesn’t cause the “high” typically associated with cannabis use.

In recent years, CBD has gained significant attention for its potential therapeutic properties. These include anti-inflammatory, analgesic, and neuroprotective effects. Consequently, researchers have begun investigating its potential benefits for various conditions, including Parkinson’s disease.

Potential Benefits of CBD for Parkinson’s Disease

Although research is still in its early stages, several studies have suggested that CBD may offer benefits for people with Parkinson’s disease. Here are some of the potential ways CBD might help:

1. Reduction of Anxiety and Depression

Anxiety and depression commonly accompany Parkinson’s disease as non-motor symptoms. Interestingly, a study published in the Journal of Psychopharmacology found that CBD may have anxiolytic (anti-anxiety) effects in humans. Therefore, CBD could potentially help alleviate some of the psychological distress experienced by PD patients.

Read the study on CBD’s anxiolytic effects

2. Improvement in Sleep Quality

Sleep disorders frequently affect people with Parkinson’s disease. Notably, a review published in the journal Medicines suggests that CBD may have therapeutic potential for treating insomnia. Consequently, improved sleep quality could significantly enhance the overall quality of life for PD patients.

Read the review on CBD and sleep disorders

3. Pain Management

Chronic pain often plagues people with Parkinson’s disease. Encouragingly, CBD has shown promise as a pain management tool in various studies. A review published in the journal Frontiers in Pharmacology discusses the potential of cannabinoids, including CBD, in pain management. Thus, CBD might offer a new avenue for PD patients struggling with chronic pain.

Read the review on cannabinoids and pain management

4. Neuroprotective Properties

One of the most exciting areas of CBD research in relation to Parkinson’s disease involves its potential neuroprotective properties. Specifically, a study published in the journal Cannabis and Cannabinoid Research suggests that CBD may have neuroprotective effects that could potentially slow the progression of PD. This finding opens up new possibilities for managing the disease’s progression.

Read the study on CBD’s neuroprotective properties

5. Reduction of Tremors and Involuntary Movements

Some preliminary research indicates that CBD might help reduce tremors and other involuntary movements associated with Parkinson’s disease. For instance, a small study published in the Journal of Psychopharmacology found that CBD significantly improved the quality of life in PD patients without parkinsonian motor symptoms. While more research is needed, these initial findings are promising.

Read the study on CBD and quality of life in PD patients

Current State of Research

While these potential benefits are promising, it’s important to note that much of the research on CBD and Parkinson’s disease remains in its early stages. Many studies have involved animal models or small sample sizes of human participants. Therefore, researchers need to conduct more extensive clinical trials to confirm these initial findings.

A comprehensive review published in the journal Medicina in 2019 examined the current evidence for cannabinoids in the treatment of movement disorders, including Parkinson’s disease. The authors concluded that while some evidence supports the therapeutic potential of cannabinoids, including CBD, more large-scale clinical trials are necessary to establish their efficacy and safety. Consequently, patients and healthcare providers should approach CBD use for PD with cautious optimism.

Read the comprehensive review on cannabinoids and movement disorders

Legal Status and Availability of CBD in the UK

In the United Kingdom, CBD products are legal as long as manufacturers derive them from hemp plants containing less than 0.2% THC. As a result, CBD products are widely available in the UK, including oils, capsules, and topical preparations. However, it’s crucial to note that companies sell these products as food supplements, not as medicines.

The Medicines and Healthcare products Regulatory Agency (MHRA) has not approved any CBD products for medicinal use in Parkinson’s disease. Consequently, while people can purchase CBD products over the counter, doctors cannot prescribe them specifically for PD symptoms. Therefore, patients should consult with their healthcare providers before incorporating CBD into their treatment regimen.

Considerations and Precautions

If you’re considering using CBD for Parkinson’s disease symptoms, keep these important factors in mind:

  • Consult your healthcare provider: It’s crucial to discuss CBD use with your doctor, especially if you’re taking other medications. CBD can interact with certain drugs, potentially altering their effectiveness or causing side effects.
  • Quality matters: Choose CBD products from reputable manufacturers who provide third-party lab testing results to ensure product quality and purity.
  • Start low and go slow: If you decide to try CBD, start with a low dose and gradually increase it while monitoring for any effects or side effects.
  • Be aware of potential side effects: While most people tolerate CBD well, some may experience side effects such as fatigue, changes in appetite, or diarrhoea.
  • Legal considerations: Ensure that any CBD product you purchase complies with UK regulations.


The potential of CBD to alleviate some symptoms associated with Parkinson’s disease represents an exciting area of research. While early studies have shown promise, researchers need to conduct more robust clinical trials to fully understand the efficacy and safety of CBD for PD.

For people living with Parkinson’s disease in the UK, CBD products are legally available as food supplements. However, it’s crucial to approach their use with caution and under the guidance of a healthcare professional. As research progresses, we may gain a clearer understanding of how CBD can effectively and safely improve the quality of life for people with Parkinson’s disease.

Remember, while CBD shows potential, patients should not consider it a replacement for conventional medical treatments for Parkinson’s disease. Instead, view it as a potential complementary approach. Always consult with your healthcare provider before making any changes to your treatment regimen. By working closely with medical professionals and staying informed about the latest research, PD patients can make the best decisions for their health and well-being.